Specialized cardiac muscle cells in the wall of the heart rapidly. Introduction to the cardiovascular system seer training. Anatomy and physiology of respiratory system overview. In this chapter, you will explore the remarkable pump that propels the blood into the vessels. Define with the more common types of cardiovascular diseases with emphasis on e tiology, mechanism, morphology and briefly to correlate the pathological aspects of diseases with. Pressures decrease as blood flows through the circulatory system due to resistance of the blood vessels. There are alarming increases in the incidence of obesity, insulin resistance, type ii diabetes, and cardiovascular disease. The questions contained in this short multiplechoice quiz will test your knowledge of pharmacology of the cardiovascular system. Efficacy and safety of novel oral p2y12 receptor inhibitors in patients with stsegment elevation myocardial infarction undergoing pci. The system is a closed circuit, which is elastic, thereby allowing movement and stresses to occur without damaging it. Heart is a coneshaped, hollow, muscular structure located in the thorax.
All animals except the simplest kinds have some type of circulatory system. Heart roughly size of human fist 250 350 grams heart. Autonomic nervous system the patient is 21 yrs old and has experienced frequent episodes of blurred vision, dizziness, faintness and syncope for as long as she can remember. The cardiovascular system and the lymphatic system collectively make up the circulatory system. Cardiovascular system pharmacology linkedin slideshare. The latter action is useful and underlies the use of the drug in patients with atrial fibrillation or flutter accompanied by a high ventricular rate, usually if combined with. Physiology and pharmacology of the cardiovascular adrenergic. Indirect actions of digitalis many of the effects of digitalis on the mechanical and electrical activity of the heart in situ, result. Ee4385, lecture notes respiratory system page 1 of 11 anatomy and physiology of respiratory system overview the primary function of the respiratory system is supplying oxygen to the blood and expelling waste gases, of which carbon dioxide is the main constituent, from the body. Cardiovascular drugs cardiovascular drugs act on the heart or blood vessels to control the cardiovascular system. During intravenous therapy with ntg, if blood pressure bp drops and ischemia is not relieved, the addition of phenylephrine will allow coronary perfusion pressure cpp to be maintained while allowing. Alright, now in this part of the article, you will be able to access the free pdf download of cardiovascular pathology 4th edition pdf using our direct links mentioned at the end of this article. This article, which forms part of the life science series, examines the cardiovascular system, focusing on the anatomy and physiology of the heart. It serves for distribution of food contents from the digestive system and of oxygen from the respiratory system to the body cells and it serves also as transport system for disposing the byproducts like c02 of the combustion process.
Mystery case dont put the cart before the horse physiology then pharmacology what will you. The quiz is scored automatically and can be taken multiple times. Jordan university of science and technology faculty of. Mesenteric blood volume increases as ventricular size, ventricular pressures, and intrapericardial pressure decrease. Ntg increases the distensibility and conductance of large arteries without chang. Cardiovascular system ans 215 physiology and anatomy of domesticated animals i.
Pdf clinical pharmacology and cardiovascular safety of naproxen. Physiology of the cardiovascular systemchapter 19 595 internodal bundles sinoatrial sa node pacemaker atrioventricular av node interatrial bundle purkinje. Sep 04, 20 the cardiac neuronal system is composed of cell stations comprising afferent, efferent, and interconnecting neurons behaving as a control system armour, 2004. To help maintain cardiovascular health, people should exercise regular. Chapter 11 clinical pharmacology of cardiovascular drugs oxford. Aortic dissection treat with nitroprusside and beta blockers. In an article published aheadofprint, leo buckley, judy cheng, and akshay desai provide an overview of the role of ace2 in cardiovascular physiology and sarscov2 virology. The cardiovascular system has ten unique characteristics that make it an unusually complicated hydraulic system. What behaviors can help maintain cardiovascular health. Beginning as a simple tube, the heart undergoes differential growth into a four chambered struc. The circulatory system is a network that carries blood throughout the body. The blood flow through the heart is described and the regulatory mechanisms of the heart are identified and discussed. Recognize the characteristics of microorganisms that cause infection of the cardiovascular system, their pathogenicity and methods of identification. The pattern of pressures in the systemic and pulmonary circulations is similary, but the pulmonary circulation operates at a much lower pressure.
The risk of these diseases is significantly reduced by appropriate lifestyle modifications such as increased physical activity. However, the exact mechanisms by which exercise influences the development and progression of cardiovascular disease are unclear. Pdf the cardiovascular system is well organized in time. Understanding how the cardiovascular system functions requires insight into a larger set of variables than that which governs the function of most pump, pipe, and fluid systems found in the world of manmade machines. Pdf chronopharmacology of cardiovascular medications.
The cardiovascular system is the railway system of the body. Acting directly upon the conduction system of the heart, digoxin slows conduction velocity through the atrioventricular av node by prolonging the refractory period. We have uploaded a genuine pdf ebook copy of this book to our online file repository so that you can enjoy a blazingfast and safe downloading experience. In this report, we discuss the physiological and pathophysiological role of endotheliumderived et1, the pharmacology of its two receptors, focusing on the. Cardiovascular physiology, pharmacology, and molecular biology 120 of blood in the splanchnic capacitance system. Introduction to the cardiovascular system flashcards quizlet. Chapter 8 cardiovascular system diseases and disorders.
It transports nutrients to all the organs and tissues to keep them supplied with energy in much the same way trains transport supplies. The blood system is the main transport system for fuel supply and disposal of body byproducts. The system is a closed circle rather than being openended and linear. Blood pressure is the force of blood against the inner walls of blood vessels anywhere in the cardiovascular system, although the term blood pressure usually refers to arterial pressure. Request pdf on jan 1, 2009, faiez zannad and others published clinical pharmacology of cardiovascular drugs find, read and cite all the research you. Cardiovascular system pharmacology education project. Affordable and search from millions of royalty free images, photos and vectors. Exercise and the cardiovascular system article pdf available in cardiology research and practice 20121. The system is filled with liquid at a positive mean pressure mean cardiovascular pressure, which exists independent of the pumping action of the heart. The cardiovascular system develops early week3, enabling the embryo to grow beyond the short distances over which diffusion is efficient for transferring o.
It is more commonly referred to in science as the cardiovascular system. The pump in this system, or the heart, simply allows the blood to flow in. Introduction to the circulatory system teachengineering. Base is directed upward dorsal and forward cranial. At the same time, it carries carbon dioxide and other wastes away from the cells. Accepts carbon dioxide and wastes from cells and delivers them to respiratory and urinary systems for disposal 3. The system of organs and structures by which blood and lymph are circulated throughout the body. Accepts oxygen, nutrients, and other substances from the respiratory and digestive systems and delivers them to cells 2. A systematic approach to cardiovascular pharmacology oxford. There is no single better word to describe the function of the heart other than pump, since its contraction develops the pressure that ejects blood into the major vessels.
Pdf the voluntary withdrawal of vioxx rofecoxib from the market in 2004, as well as the 2005 and 2014 us fda advisory committee. The ans outflow to the heart and to the peripheral circulation is regulated by cardiovascular reflexes. They are used to treat a variety of conditions from hypertension to chronic heart failure. Cardiovascular system the cardiovascular system is, in the simplest form, a system that consists of a pump, pipes, and a fluid system. The cardiovascular physiology and pharmacology of endothelin1. For instance, although it infests host cells through ace2, how the virus impacts the reninangiotensinaldosterone system raas and vice versa is not known. Here is what we have learned from introduction to the cardiovascular system the cardiovascular system consists of the heart, which is a muscular pumping device, and a closed system of vessels called arteries, veins, and capillaries. Larger arteries and veins are continuous with the heart as its base. Chronic diabetic glomerulopathy doc are ace inhibitors. Cardiovascular system stock photos and images 123rf.
Home explore pharmacology drugs acting on cardiovascular system. Institute of pharmacology and toxicology, university of heidelberg, mannheim, germany. Apr 20, 2016 the cardiovascular system is able to fight disease by providing the body with white blood cells that fight pathogens and other intruders in the body. Arterial blood pressure rises and falls following a pattern established by the cardiac cycle. Other parts of the blood like platelets and red blood cells help seal wounds with scabs to prevent additional bacteria from entering, and the antibodies in blood know to attack pathogens to. Antianginal drugs the three main types of angina are. The human circulatory system supplies the cells of the body with the food and oxygen needed to survive. Clinical pharmacology of cardiovascular drugs request pdf. The lymph, lymph nodes and lymph vessels form the lymphatic system. Diseases of the cardiovascular system include atherosclerosis and hypertension.
Cardiovascular pathology 4th edition pdf free download. There are several classes of established lipidlowering, or antihyperlipidemic drugs available to the prescriber. Vertebrates have a closed circulatory system, meaning the blood is repeatedly cycled throughout the body inside a system of pipes. After completing this exercise, you will be able to name major organs of the cardiovascular system and some of the major arteries and veins use the reference on the left to locate controls and areas referred to in the text below.
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